Nicolas Rode

Nicolas Rode

session, year:
2014 1st

Former fellow

Receiving laboratory:
AGAP Genetic Improvement and Plant Adaptation, Montpellier

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Download Curriculum Vitae

Mobility project

Investigation of selection gradients on phenology and local adaptation in a highly selfing species using Hi-seq metabarcoding

In the context of unprecedented anthropogenic forcing in the living world, the mechanisms and speed of evolution remain key to understand the dynamics of adaptation. Measuring selection in natural populations allows identifying the phenotypic traits and the environmental factors involved in the adaptive process. This project aims at measuring the fitness of a genotype as a change in frequency over its entire life cycle. This can easily been done in predominantly self-fertilizing species. I am using population reciprocal transplant experiments to investigate local adaptation and selection on flowering time in natural populations of the model legume species Medicago truncatula.

Biography & research interests

I obtained a Bioscience Master from the Ecole Normale Supérieure of Lyon and I did a PhD in evolutionary ecology at the University Montpellier II. During my PhD, I quantified contemporary microevolution in natural populations of brine shrimp, a non-model organism using statistical analyses of life history and fitness data (generalized linear models, survival analyses). In my first post-doctorate at the University of Ottawa, I investigated indirect genetic effects and condition-dependent sex in the model filamentous fungus Aspergillus nidulans. As an AgreenSkills fellow at the UMR AGAP (Montpellier), I investigated selection gradients and local adaptation in the model plant Medicago truncatula. I also developed a model for assessing the accuracy of haplotype frequency estimation when sequencing multiple individuals together (pool-sequencing) under various experimental designs. Since February 2017, I am a CEMEB fellow working with Arnaud Estoup at the CBGP-INRA (Montpellier). I investigate insecticide resistance in the pest Drosophila suzukii using both experimental evolution and next-generation sequencing techniques.


Selected publications

Rode N.O., Holtz Y., Loridon K., Santoni S., Ronfort J. & Gay L., 2018. How to optimize the precision of allele and haplotype frequency estimates using pooledsequencing data, Molecular Ecology Resources. Doi. org/10.1111/1755-0998.12723.

Holtz Y., Bonnefoy M., Viader V., Ardisson M., Rode N.O., Poux G., et al., 2017. Epistatic determinism of durum wheat resistance to the wheat spindle streak mosaic virus. Theor. Appl. Genet., 130, 1491-1505.

Rode N.O., Soroye P., Kassen R., Rundle H.D., 2017. Air-borne genotype by genotype indirect genetic effects are substantial in the filamentous fungus Aspergillus nidulans. Heredity, 119, 1-7.

Nougué O, Rode NO, Jabbour-Zahab R, Ségard A, Chevin LM, Haag CR, Lenormand T., 2015. Automixis in Artemia: solving a century-old controversy. Journal of Evolutionary Biology. Doi: 10.1111/jeb.12757.

Rode N.O., Lievens E.J.P. , Flaven E., Segard A., Jabbour- Zahab R., Sanchez M.I. & Lenormand T., 2013. Why join groups? Lessons from parasite-manipulated Artemia. Ecology Letters, 16, 493-501. † Equal contribution

Awards & patents

2013: Young Investigator Prize from the French Ecological Society (750€)

2012: Young Investigator Prize from the Bettencourt Foundation (25 000€)


Realised fitness, selection gradient, local adaptation, selfing, metabarcoding, Medicago truncatula