BelgiumCountry of destination:
The preservation and maintenance of biodiversity is essential for the sustainable production of food resources. In birds, conservation of reproductive cells such as semen and primordial germinal cells (PGCs) are major tools for ex situ management of genetic diversity. My mobility project goal is to study the bird reproductive cells proteome and to identify reproduction quality protein biomarkers/profiles to reliably define the reproductive/differentiation ability of these cells either fresh or preserved, and to optimize preservation techniques. Additional complementary epigenetic analysis will be performed as we expect that epigenetic reprogramming will have further consequences on reproductive capacities and early embryonic development.
I got my degree in Veterinary Medicine at the University of Murcia, Spain in the year 2005, and soon decided to become a researcher in Veterinary Clinical Biochemistry. My PhD project had the purpose of creating and validating new immunoassays to determine the biomarker Serum Amyloid A in pigs’ serum, saliva and meat juice. During this project I collaborated with scientists worldwide (Spain, UK, Belgium, Austria and New Zealand). I got my PhD in 2010, and stayed for one extra year at the University of Murcia (Spain) as a research assistant working on salivary stress biomarkers. In January 2012 I got a postdoctoral position at the Bioengineering Faculty of KU Leuven (Belgium) on pig intestinal health. I started applying high performance and conventional proteomics with the collaboration of GIGA Liège (Belgium), and realized the huge possibilities of this kind of analysis in animal production and breeding. Thereafter, I spent more than two years at INRA-Val de Loire applying proteomics to understand the molecular basis of male fertility in birds. I recently got recruited as permanent researcher at the INRA Toulouse (Toxalim) to work on mycotoxicology and pig intestinal immunology.
Soler L., Labas V, Thélie A, Grasseau I, Teixeira-Gomes AP, Blesbois E., 2016. Intact Cell MALDI-TOF MS on Sperm: A Molecular Test For Male Fertility Diagnosis. Mol Cell Proteomics. 15: 1998-2010. Doi: 10.1074/mcp. M116.058289.
Soler L., Miller I., Hummel K., Razzazi-Fazeli E., Jessen F., Escribano D., Niewold T., 2016. Growth promotion in pigs by in-feed oxytetracycline coincides with anti-inflammatory changes in the serum proteome. Electrophoresis. 37: 1277-1286. Doi: 10.1002/ elps.201500529.
Ceciliani, F., Soler, L., Grilli, G., Marques, AT., Giudice, C., Lecchi, C., 2015. The localization and differential expression of Serum Amyloid A in bovine liver and adipose tissue depots. Vet. Immunol. Immunopathol., 168(1-2), 35-39.
Soler L., Moreno A., Niewold T., Garrido J.J. 2014. Proteomic approaches to study the pig gastrointestinal system. Current Protein & Peptide Science, 15: 89-99.
European awarded Doctoral Thesis in Veterinary Medicine entitled “New contributions on porcine Serum Amyloid A” June 2010. Summa cum laude and extraordinary mention by the Veterinary School of the University of Murcia.
National Award for the Outstanding Graduate of the Year in Veterinary Medicine, awarded by the Ministry of Science and Education of Spain, 2006.
Best research communication award in the European Society of Veterinary Clinical Pathologists Congress. Cambridge 2006.
Best oral presentation of a young researcher. 3rd managing committee meeting and 2nd meeting of working groups 1, 2 & 3 of COST action FA1002. Vilamoura (Portugal). April 2012.
Best oral presentation of session “Advancing methodology for farm animal proteomics and bioinformatics”. 4th managing committee meeting and 3rd meeting of working groups 1, 2 & 3 of COST action FA1002. Kosice (Slovakia). April 2013.