Aude Remot

Aude Remot


Agreenskills
session, year:
2013 1st

Status:
Former fellow

Receiving laboratory:
Flemish Institute for Biotechnology, Ghent

Country of origin:

France

Country of destination:

Belgium

Last available contact

Email(s):
aude.remot@jouy.inra.fr

Website(s):
http://www.irc.ugent.be/index.ph...

CV:
Download Curriculum Vitae

Mobility project

Lung flora and neonatal immunity

I worked 6 months in Gent (Belgium) in the Laboratory of Immunoregulation and Mucosal Immunology, headed by Pr. Bart Lambrecht, in the group managed by Pr. Hamida Hammad. They are internationally recognized as expert in lung immunology, respiratory disorders and dendritic cell-epithelium cross-talk. Their competencies in immunology are an important added-value for my research project on the influence of lung microbiota on neonatal immunology. This mobility period during my post-doctorate will boost my education and help to enhance my international network.

Biography & research interests

My passion for science and immunology is the reason why I have decided to specialize in life-science research. After my Master degree on Infectiology and Vaccinology, I succeeded a challenging competition to obtain a 5-years special contract financed by INRA, called «Young Scientist Contract», which gave me the opportunity to build myself a coherent career plan. During my PhD, I worked in the Molecular Virology and Immunology unit (INRA) on the neonatal sensitivity to a respiratory virus. For my post-doctoral period (started in March 2013), I pursued in this field and explored a new and promising area: the impact of the development of the lung microbiota on neonatal immunity (with a special interest for lung epithelium and dendritic cells). To obtain the expertise in microbiology required for the subject, I decided to work in the MICALIS INRA department, in an internationally recognized team dealing with commensals-host interactions (ProbiHôte). Thanks to the AgreenSkills mobility allowance, I spent 6 months in Ghent (Belgium), in Hamida Hammad’s & Bart Lambrecht's research group (immunoregulation and mucosal immunology), experts in lung immunity and asthma. These innovative and multi-disciplinary projects gave me the opportunity to become an expert in the field of lung microbiota and immunity of the respiratory tract. In 2015, I obtained a permanent researcher position at INRA in the UMR Infectiology and Public Health, in Tours-Nouzilly. My research activities are now focusing on the physiopathology of bovine tuberculosis in cattle, with a special interest for lung immunity and innate responses.

Selected publications

A. Remot, D. Descamps, ML. Noordine, et al., 2017. Bacteria isolated from lung modulate asthma susceptibility in mice. ISME J, 11(5):1061-1074.

A. Remot, D. Descamps, L. Jouneau, et al., 2016. Flt3 ligand improves the innate response to respiratory syncytial virus and limits lung disease upon RSV reexposure in neonate mice. Eur J Immunol. 46(4):87484.

MA. Rameix-Welti, R. Le Goffic, PL. Hervé, J. Sourimant, A Remot, et al., 2014. Visualizing the replication of respiratory syncytial virus in cells and in living mice. Nature Communications, 5:5104. Doi: 10.1038/ ncomms6104.

A. Remot, X. Roux, C. Dubuquoy, et al., 2012. Nucleoprotein Nanostructures Combined with Adjuvants Adapted to the Neonatal Immune Context: a Candidate Mucosal RSV Vaccine. PLoS ONE. 7(5):e37722. Doi: 10.1371/journal.pone.0037722.

A. Remot*, X. Roux*, M. Abolhassani, et al., 2011. Neonatal pulmonary immune responses show a deficit of the conventionnal dendritic cell subset and a shift of cytokines and transcription factors towards Th2. European Journal of Immunology. 41(10):2852-61. Doi: 10.1002/ eji.201041224. (*co first author)

Awards & patents

In 2015, I obtained a 1-year “Prematuration” grant based on the patentability of my post-doctoral work. *

In 2014, I won a presentation award during the Word Immune Regulation Meeting (Davos, VIII WIRM, Workshop 6: Dendritic Cells)

In 2012, I received a travel award to attend the European Congress of Immunology (ECI2012) from the French Society for Immunology (SFI) and the French Academy of Sciences.

In 2011, I received the first poster prize during my doctoral school annual meeting, which gave me the opportunity to present my work during a Cold Spring Harbor congress in New York the same year.

Co-inventor (45%), INPI publication number FR3047010

Talks in annual meetings

Lung flora and neonatal immunity
2013 / P2 Tissue and Individual / by Aude Remot / Fellows Speed Presentation

Keywords

Microbiota, lung, immunology, neonatal period, respiratory disorders, immunomodulation