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Ashkan Madadlou

Ashkan Madadlou

session, year:
2017 1st


Receiving laboratory:
STLO Science and Technology of Milk and Eggs, Rennes

Country of origin:

Iran, Islamic Republic of

Country of destination:


Last available contact

Download Curriculum Vitae

Mobility project

Food-based carriers for the delivery of pancreatic enzymes to elderly for restoring digestion and tackling malnutrition

European population is ageing. It is estimated that the proportion of old population (individuals aged>65 years) will grow from 16% in 2010 to 29% by 2060. Malnutrition is correlated with morbidity and mortality of elderly people. Malabsorption of nutrients due to pancreatic insufficiency is amongst the reasons that cause weight loss in the elderly and several human trials have clearly established that the pancreatic exocrine secretion does decline in advanced age. This project aims at developing innovative semi-solid foods and beverages specifically dedicated to deliver pancreatic secretions and tackle elderly malnutrition. An emulsion will be fabricated to deliver both highly nutritive proteins and pancreatic enzymes in the gastrointestinal tract. Whey protein microgels (WPMs) which are sub-micron dense spheres formed through heating whey proteins can deliver remarkable amounts of nutritive proteins to geriatric persons. Accompanied by supplementing with WPMs, pancreatic enzyme replacement therapy would increase wellness of older individuals. After optimization of the manufacture process, composition and stability of the formula, the nutritional performances of the products will be assessed through in vitro dynamic gastrointestinal digestion with the DIDGI® simulator, using a model of the elderly gastrointestinal tract that will be developed during this project.


Biography & research interests

I obtained BSc (in 2003), MSc (in 2005) and PhD (in 2009) degrees in Agricultural Engineering-Food Science and Technology. I moved to France to work as a researcher for the French National Institute for Agricultural Research (INRA) in STLO Research Unit.

Selected publications

Vahedifar A., Madadlou A., Salami M., 2018. Influence of seeding and stirring on the structural properties and formation yield of whey protein microgels. International Dairy Journal. 79, 43-51.

Koshani, R., Madadlou, A., 2018. A viewpoint on the gastrointestinal fate of cellulose nanocrystals. Trends in Food Science and Technology, 71: 268-273. Doi: 10.1016/j.tifs.2017.10.023.

Madadlou A., Abbaspourrad A., 2017. Bioactive whey peptide particles: An emerging class of nutraceutical carriers. Critical Reviews in Food Science and Nutrition. Doi: 10.1080/10408398.2016.1264064.

Nooshkam M., Madadlou A., 2016. Maillard conjugation of lactose with potentially bioactive peptides. Food Chemistry. 192, 831-836.

Madadlou A., Jaberipour S. & Eskandari M.H., 2014). Nanoparticulatation of enzymatically cross-linked whey proteins to encapsulate caffeine via microemulsification/ heat gelation procedure. LWT-Food Science & Technology, 57, 725-730.

Talks in annual meetings

Identification of dietary modulators of cognitive function in ageing using metabolomics discovery
2018 / P4 Nutrition,P5 Products and Technology / by Ashkan Madadlou / Fellows Speed Presentation
Food carriers to restore digestion in the elderly (scientific report)
2019 / P4 Nutrition,P5 Products and Technology / by Ashkan Madadlou / Fellows Speed Presentation


Malnutrition, Malabsorption, Whey protein, Microfluidics, Double emulsion, Gellan, ?Spontaneous emulsification, Carbonate particle. ?